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Inhaled Ventavis® (iloprost) Inhalation Solution Breathe In Your Second Chance For Patients with Pulmonary Arterial Hypertension with NYHA Class III or IV Symptoms
     Signs and Symptoms
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PAH Learning Center
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Signs and Symptoms of PAH

Signs and symptoms of pulmonary hypertension may not be obvious at first, but they can worsen over time and can begin to limit daily activities. Common PAH symptoms include1:
Some of the early symptoms of PAH that you may experience:
  • Breathlessness or shortness of breath
  • Chronic fatigue
  • Dizziness
  • Fainting
  • Swollen ankles and legs
  • Chest pain, especially during physical therapy

Symptoms and classification
The New York Heart Association (NYHA) functional classification system is an important method your doctor may use to measure the severity of your symptoms to decide what type of treatment is right for you.2

  • Class I
  • No limitations in usual physical activity and very mild symptoms.
  • Class II
  • Normal activity causes some shortness of breath, tiredness, chest pain, or lightheadedness.
  • Class III
  • Even mild activity causes shortness of breath, tiredness, chest pain, or lightheadedness, and is significantly limited because of these symptoms.
  • Class IV
  • Shortness of breath, tiredness, chest pain, and lightheadedness, even at rest.

Read about:

  • What is PAH?
  • Diagnosing PAH
  • Treating PAH
  • Living with PAH
  • PAH Learning Center
  • Useful Links

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    IMPORTANT SAFETY INFORMATION:
    Because it lowers your blood pressure, Ventavis may cause dizziness, lightheadedness, and fainting. With Ventavis, the most common side effects are reddening of the face caused by dilation of blood vessels (flushing), increased cough, low blood pressure (hypotension), headaches, nausea, spasm of the jaw muscles that causes trouble opening your mouth, and fainting (syncope); other serious adverse events reported with the use of Ventavis include congestive heart failure, chest pain, supraventricular tachycardia, dyspnea, peripheral edema, and kidney failure. Before you start taking Ventavis, talk to your doctor to make sure you understand the side effects you might get.

    1. McLaughlin V, McGoon MD. Pulmonary arterial hypertension. Circulation. 2006;114:1417-1431.
    2. 1994 revisions to classification of functional capacity and objective assessment of patients with diseases of the heart. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=1712. Accessed May 6, 2009.
    3. Simonneau G, Galie N, Rubin LJ, et al. Clinical classification of pulmonary hypertension. J Am Coll Cardiol. 2004;43:5S-12S.

    I-neb AAD is a registered trademark of Philips Respironics.

    Please see full Prescribing Information

    For more information about
    Ventavis, please call
    1-866-ACTELION (1-866-228-3546).

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