• Why Take Ventavis?

• Start and Stay on Therapy

•      Getting Started

•      Understanding Your Role

•      ABCs: Making the Most of
       Ventavis Treatments

• Ventavis FAQs

• Taking Ventavis with the
  I-neb AAD

• Resources

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  Professionals

PAH Pathways

Helpful services from PAH Pathways are available to you with your Ventavis prescription. PAH Pathways is Actelion’s patient service and support program— and your one point of contact for questions about Ventavis, access to insurance coverage and financial assistance for eligible patients.

PAH Pathways is with you every step of the way

When your Ventavis prescription is written, it goes to PAH Pathways. Why does PAH Pathways get it first? Because a Ventavis prescription cannot be filled at your neighborhood pharmacy. It must be dispensed through a specialty pharmacy that is part of the Ventavis network. The PAH Pathways Counselors will ensure that it goes to an appropriate pharmacy and will work with your insurance provider to help answer your questions.

If you have any questions about PAH Pathways, call toll-free, 1-866-ACTELION (1-866-228-3546) Monday through Friday, 9 AM to 8 PM (Eastern time), 6 AM to 5 PM (Pacific time).

Is Ventavis covered by insurance?

Every insurance company is different, but most plans cover at least some of the cost of Ventavis and the I-neb AAD System. Our PAH Pathways Counselors will help ensure that you get Ventavis with the least financial burden possible.

You may want to contact the CVC, an independent, nonprofit third-party organization, for information about how to receive financial assistance. If you qualify, the CVC may be able to offer you assistance with insurance policy premiums, emergency financial needs, and peer support programs. Contact the CVC toll-free at 1-888-267-1440 or visit www.caringvoice.org

Paying for therapy is a concern for many people. Ventavis is paid for by many different health insurance plans. PAH Pathways and your specialty pharmacy will work with your insurance company to get Ventavis for you. If you don’t have health insurance, Actelion—the maker of Ventavis—may be able to help. PAH Pathways, Actelion’s service and support program, has financial assistance available to help eligible people pay for their therapy. Visit www.PAHPathways.com or call 1-866-ACTELION (1-866-228-3546) to learn more.

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What is Ventavis?

Ventavis is a prescription medicine used to treat adults with certain kinds of severe pulmonary arterial hypertension (PAH), a condition in which blood pressure is too high in the blood vessels between the heart and the lungs. Ventavis may improve your ability to exercise and your symptoms for a short time by lowering your blood pressure and opening up the blood vessels in your lungs.

• In the key clinical study, Ventavis showed clinical improvement as defined by 3 specific measurements: ability to exercise as measured by the 6-minute walk test, symptoms (NYHA Functional Class), and decrease in the worsening of PAH symptoms.
• Ventavis is a medication you breathe in through a special device called the I-neb Adaptive Aerosol Delivery (AAD) System.

The study showing Ventavis is effective included mainly patients with NYHA Functional Class III-IV PAH. In these patients, PAH was caused by unidentified or hereditary factors (65%) or connective tissue diseases (23%).

Ventavis has not been studied in children younger than 18 years old.

What is the most important information I should know about Ventavis?

Ventavis may not be right for you. Before taking Ventavis, tell your doctor about all of your medical conditions, including if you have liver or kidney problems; are pregnant, or plan to become pregnant; or are breast-feeding. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take medicines used to treat high blood pressure or heart problems or medicines that lessen blood clotting (warfarin, Coumadin, Jantoven). Ventavis and other medicines may affect each other, causing side effects.

What are the possible side effects of Ventavis?

• Ventavis may cause side effects, including feeling dizzy, lightheaded, and faint. If you have any of these side effects, you should stand up slowly when you get out of chairs or bed. Tell your doctor if your fainting gets worse during treatment with Ventavis. Your doctor may need to change your dose or treatment.
• Do not drive a car or operate any tools or machines if dizziness or fainting from low blood pressure is a problem for you.
• You may have trouble breathing after taking Ventavis, because it may cause the muscles around your airway to tighten (bronchospasm). Get emergency help right away if you have trouble breathing.
• The most common side effects of Ventavis include red face (flushing), increased cough, low blood pressure, headaches, nausea, spasm of your jaw muscles that makes it hard to open your mouth, and fainting.

Talk to your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Ventavis. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Please see full Prescribing Information