Specialty Pharmacy

Once you have decided that Ventavis® (iloprost) Inhalation Solution is right for your patient and have completed the Ventavis enrollment forms, a specialty pharmacy will be selected based upon your patient's in-network insurance status. A Ventavis-trained healthcare professional will contact your patient and discuss the following: insurance coverage and reimbursement for Ventavis and for the I-neb Adaptive Aerosol Delivery (AAD) System.

At treatment initiation, a training session will be set up with a specialty pharmacy nurse. Training can take place at your patient's home, in your office, or at the local hospital. After your patient's training session, the specialty pharmacy will arrange a follow-up session to discuss any other questions or issues your patient may have regarding Ventavis or the I-neb AAD System.

Participating specialty pharmacies have a 24-hour emergency service. If your patients have a problem with their I-neb AAD System, they should contact the specialty pharmacy immediately to arrange delivery of a replacement device.

This service is available on weekends as well.

Read about:

Respironics and I-neb Adaptive Aerosol Delivery (AAD) are trademarks of or belonging to Koninklijke Philips Electronics N.V.

The Ventavis 20 mcg/mL concentration order form is intended for patients who are maintained at the 5 mcg dose and who have repeatedly experienced extended treatment times which could result in incomplete dosing. Ventavis 10 mcg/mL ampules are still available. Ventavis should be taken 6 to 9 times daily, at least 2 hours apart.

For more information about Ventavis, please call 1-866-ACTELION (1-866-228-3546).

Indication and Important Safety Information

 OPEN CLOSE

Indication:

Ventavis is indicated for the treatment of pulmonary arterial hypertension (PAH) (WHO Group 1) to improve a composite endpoint consisting of exercise tolerance, symptoms (NYHA Class), and lack of deterioration. Studies establishing effectiveness included predominantly patients with NYHA Functional Class III-IV symptoms and etiologies of idiopathic or heritable PAH (65%) or PAH associated with connective tissue disease (23%).

Important Safety Information

  • Hypotension leading to syncope has been observed; Ventavis should therefore not be initiated in patients with systolic blood pressure less than 85 mmHg.
  • Stop Ventavis immediately if signs of pulmonary edema occur; this may be a sign of pulmonary venous hypertension.
  • Ventavis inhalation may cause bronchospasm and patients with a history of hyperreactive airway disease may be more sensitive.
  • Serious adverse events reported at a rate of less than 3% included congestive heart failure, chest pain, supraventricular tachycardia, dyspnea, peripheral edema, and kidney failure. Vital signs should be monitored while initiating Ventavis.
  • In clinical studies, the most common adverse events occurring more often (≥6%) in Ventavis-treated patients than in patients taking placebo included vasodilation (flushing) (27% vs 9%), cough (39% vs 26%), headache (30% vs 20%), trismus (12% vs 3%), and insomnia (8% vs 2%).
  • Ventavis has the potential to increase the hypotensive effect of vasodilators and antihypertensive agents.
  • Ventavis also has the potential to increase risk of bleeding, particularly in patients maintained on anticoagulants.

Please see full Prescribing Information.