Inhaled Ventavis® (iloprost) Inhalation Solution Privacy Policy  |  Terms & Conditions  |  Contact Us  |  Site Map  |  Important Safety Information   

*Indication

Ventavis is indicated for the treatment of pulmonary arterial hypertension (PAH) (WHO Group 1) to improve a composite endpoint consisting of exercise tolerance, symptoms (NYHA Class), and lack of deterioration. Studies establishing effectiveness included predominately patients with NYHA Functional Class III-IV symptoms and etiologies of idiopathic or heritable PAH (65%) or PAH associated with connective tissue disease (23%).

Inhaled Ventavis® (iloprost) Inhalation Solution
PAH Pathways - Actelion Services & Support
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Actelion Pharmaceuticals US, Inc.
5000 Shoreline Court, Suite 200
South San Francisco, CA 94080
Phone 1-866-ACTELION (1-866-228-3546)
Fax 1-415-268-9515
Monday through Friday,
9 AM to 8 PM (ET)
6 AM to 5 PM (PT)

Medical Information

Patients should always talk with their healthcare team first if there are any questions about their individual treatment.

For further medical information on Actelion treatments or pulmonary arterial hypertension (PAH), please contact our Medical Information Department by calling 1-866-ACTELION (1-866-228-3546), sending a fax to 1-415-268-9515.

The hours of operation for the Medical Information Department are 6:00 a.m. to 4:00 p.m. PST, Monday through Friday, excluding holidays.

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This form is not for reporting information about any medication side effects. To report suspected adverse reactions, contact Actelion at 1-866-ACTELION (1-866-228-3546), or the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch

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IMPORTANT SAFETY INFORMATION

Hypotension leading to syncope has been observed; Ventavis should therefore not be initiated in patients with systolic blood pressure less than 85 mmHG. Stop Ventavis immediately if signs of pulmonary edema occur; this may be a sign of pulmonary venous hypertension. Ventavis inhalation may cause brochospasm and patients with a history of hyperreactive airway disease may be more sensitive. Serious adverse events reported at a rate of less than 3% included congestive heart failure, chest pain, supraventricular tachycardia, dyspnea, peripheral edema, and kidney failure. Vital signs should be monitored while initiating Ventavis. In clinical studies, common adverse reactions due to Ventavis included vasodilation (flushing), cough, headache, trismus, and insomnia. Ventavis has the potential to increase risk of bleeding, particularly in patients maintained on anticoagulants.

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